Electricity
and Magnetism
Electromagnetism was first discovered in the 1800s by the
English physicist Michael Faraday, who determined that a
magnetic field could be generated by running an electric
current through a wire coil. Conversely, a changing magnetic
field can generate an electric voltage; the magnetic field
must change to have any electrical effect (hence, the term
pulsating electromagnetic field therapy, which generates
rising and falling levels of a magnetic field.)
The biological
effects of pulsating electromagnetic fields are hypothesized
to be due to electrical rather than magnetic forces. Magnetism
generates a voltage in tissue according to the equation:
V = n x a x dB/dt
V = Voltage
n = number
of turns in the electromagnetic coil
a = area of
the loop
dB/dt = The
rate of change of magnetic field with respect to time, with
B representing the strength of the magnetic field (in Teslas).
For example, if B goes from zero to 1 Tesla in 1 millisecond,
then dB/dt = 1000 Teslas/sec.
Based on this
equation, a static magnetic field cannot generate an electrical
voltage, as the dB/dt component of the equation, is zero,
as is the voltage induced by the field. Thus, any effects
of a static magnetic field on tissue cannot be electrical
in nature.
Pulsating Electromagnetic
Field Therapy
Extracellular
matrix synthesis and repair are subject to regulation both
by chemical agents (such as cytokines and growth factors)
and physical agents, principally mechanical and electrical
stimuli. The precise nature of such electromechanical signals
is not known, however. In bone, mechanical and electrical
signals may regulate the synthesis of extracellular matrix
by stimulating signaling pathways at the cell membrane.6,7
In soft tissue, alternating current electrical fields induce
a redistribution of integral cell membrane proteins which,
hypothetically, could initiate signal transduction cascades
and cause a reorganization of cytoskeletal structures. 8
However, the hypothesis that electrical signals may be responsible
for information transfer in or to cells has neither been
proved nor disproved.
There is ample
evidence that electrical activity exists in the body at
all times. For example, electrical currents can be measured
in the beating heart and are also generated in the production
of bone. Endogenous electrical current densities produced
by mechanical loading of bone under physiologic conditions
approximate 1 Hz and 0.1 - 1.0 microA/cm2 .9 Thus, it is
theorized that application of an appropriate electrical
current, either directly through wires or indirectly through
induction by a magnetic field, may affect tissues in several
ways. The word appropriate in the preceding sentence is
important since cells and tissues respond to a variety of
electrical signal configurations in ways that suggest a
degree of specificity for both the tissue affected and the
signal itself.
The most widely
studied application of electromagnetic field therapy in
human medicine is in fracture therapy. Although the mechanisms
remain undetermined, several studies report that electrical
fields generated by pulsating electromagnetic field therapy
stimulate biologic processes pertinent to osteogenesis10,11,12
and bone graft incorporation. 13,14 This form of therapy
is approved for the treatment of delayed and non-union fractures
in humans in the U.S. by the United States Food and Drug
Administration. Effectiveness of the treatment is supported
by at least two double-blind studies.15,16 Pulsating electromagnetic
field therapy, however, delays the healing of fresh experimentally
induced fractures in rabbits.17
Pulsating electromagnetic
field therapy has also been evaluated in the treatment of
soft tissue injuries, with the results of some studies providing
evidence that this form of therapy may be of value in promoting
healing of chronic wounds (such as bedsores)18 , in neuronal
regeneration,19,20 and in many other soft tissue injuries.21,22
results of a recent study in an experimental Achilles tendinitis
model in rats indicated that there was an initial decrease
in water content in injured tendons treated with pulsating
electromagnetic field therapy but that all treated groups
were equal to controls by 14 days.23The limited value of
this form of therapy in the treatment of tendon injuries
may be due in part to the lack of significant electrical
activity in tendons, activity that could be altered by a
pulsating electromagnetic field.
In contrast,
a number of investigators have been unable to show any effect
of low-level electromagnetic fields on tissue healing. One
study, for example, failed to identify any beneficial effect
of applying a magnetic field to a non-healing fracture24
and concluded that the long periods of immobilization and
inactivity required for the application of the magnetic
field therapy were just as likely to be responsible for
tissue healing.
Criticisms
of pulsating electromagnetic field studies include: some
of the studies are poorly designed; independent trials have
not been conducted to confirm positive results; and the
electrical fields induced by the machines are several orders
of magnitude lower than are required to alter the naturally
occurring electrical fields that exist across biological
membranes.25 Even proponents of the therapy concede that
much work needs to be done to optimize such variables as
signal configuration and duration of treatment before pulsating
electromagnetic field therapy can be generally recommended.26
Static Magnetic
Field Therapy
Magnetic devices
that radiate an unchanging magnetic field are available
in a variety of configurations such as pads, bandages, and
even magnetic mattresses. Scientific studies do not support
claims of efficacy. Furthermore, a mechanism of action by
which such devices might exert these effects remains elusive.
Because static magnetic fields do not change, there can
be no electrical effect. Hypotheses for an effect of a static
field include influencing the electronic spin rate states
of chemical reaction intermediates27,28 and influencing
cyclical changes in the physical state(s) of water.29 Importantly,
neither of these proposed effects has been demonstrated
in biological systems under physiological condition.30
In spite of
a lack of demonstrable mechanism of action, proponents of
applying static magnetic field therapy to injured or painful
tissues generally attribute their alleged effects to an
increase in local blood circulation. Unfortunately, the
scientific evidence in supporting this hypothesis is tenuous
at best.
Blood, like
all tissues, contains electrically charged ions. A physics
principle known as Faraday's Law states that a magnetic
field will exert a force on a moving ionic current. Furthermore,
an extension of Faraday's law called the Hall effect states
that when a magnetic field is placed perpendicular to the
direction of flow of an electric current, it will tend to
deflect and separate the charged ions. While the deflection
of ions will be in opposite directions depending on the
magnetic pole encountered and the charge of the ion, this
force is not based on the attraction or repulsion of like
and unlike charges.
The Hall effect
implies that when a magnet is placed over flowing blood
in which ionic charges (such as Na+ and Cl-) exist, some
force will be exerted on the ions. Furthermore, the separation
of ionic charges will produce an electromotive force, which
is a voltage between points in a circuit. In theory, this
produces a very small amount of heat. These physical effects,
which do exist, provide the basis for a quasi-scientific
theory to account for the purported effects of static magnetic
field therapy. For example:
When
a magnetic field with a series of alternating North and
South poles is placed over a blood vessel, the influence
of the field will cause positive and negative ions (for
example, Na+ and Cl-) to bounce back and forth between the
sides of the vessel, creating flow currents in the moving
blood not unlike those in a river. The combination of the
electromotive force, altered ionic pattern, and the currents
causes blood vessel dilation with a corresponding increase
in blood flow. 31
The problem
with using Faraday's law and the Hall effect to explain
the purported effects of static magnetic pads is that the
magnitude of that force applied by the field is infinitesimally
small. Two facts account for the lack of effect. First,
the magnetic field applied to the tissue is extremely weak.
Second, the flow of the ionic current (i.e., the blood)
is extremely slow, especially when compared to the flow
of electric current. However, it is possible to estimate
the forces applied to flowing blood by a weak magnetic fieldas
long as the strength of the magnetic field applied, the
velocity of the flowing blood, and the number of the ions
in the blood are known.
Magnetic field
strength is measured in one of two units: 1 Tesla = 104
Gauss. The magnetic field strength of a Norfield's MAGNETIChockwrapTM(for
horses) measured at California Institute of Technology had
a field strength of 270 Gauss at the level of the pad and
1 Gauss at a distance of 1 cm from the pad. Tissues purportedly
affected by the pads lie at least 1 cm away from them; 1
Gauss is approximately the magnetic field strength of the
earth.32 Promotional information for Bioflex pads asserts
an "independent laboratory" has measured the field
strength of their pads at 350 Gauss and that "optimum"
field strength for the purported healing effects is less
than 500 Gauss.33 Regardless, these are very weak magnetic
fields.
Considering
the applied magnetic field at 250 Gauss (0.025 Tesla) and
the velocity of blood flow v as 1 cm/sec (0.01 m/sec), the
electric field to which an ion in the blood is exposed can
be calculated as:
E
= v x B = 2.5 x 10-4 Volts/meter/sec
Hence, the
change in electric potential (a psuedo-Hall effect) across
a 1 mm diameter blood vessel can be estimated at a minuscule
2.5 x 10-7 Volts.
Ions of opposing
charges will move in opposite directions when moving through
a static magnetic field. The separation of charges, known
as the drift velocity, can also be calculated. In the case
of Na+ and Cl- ions in flowing blood under the influence
of a 250 Gauss magnetic field, the increased separation
of the positive sodium and the negative chloride ions will
be about 0.2 Angstroms per second, or about 1/10 the diameter
of an atom. This can be compared with the random drift distance
in one second that results from the thermal agitation imparted
by the heat of the horse's body of about 0.25 mm/sec. Stated
in another fashion, the ions will travel farther from thermal
agitation than from the 250 Gauss magneto-electrical field
drift by a factor of about 10 million.34
Any magnetic
forces generated by a static field affecting fluid movement
in blood vessels would have to overcome both the normal,
pressure-driven turbulent flow of blood propelled by the
heart and the normal thermal-induced Brownian movement of
the particles suspended in the blood. Given the strong physical
forces that already exist in a blood vessel, any physical
forces generated by a static magnetic field on flowing blood,
particularly those as weak as those associated with therapeutic
magnetic pads, are extremely unlikely to have a biological
effect.
Magnetic Pad
Design
At least one
manufacturer of magnetic pads (Magnaflex/BioflexTM) asserts
that the effect of charge separation can be increased by
alternating north and south magnetic poles. Alternating
magnetic poles are most commonly seen in refrigerator magnets.
By alternating the magnetic poles, an increased magnetic
gradient is created, which increases the ability of the
magnets to stick to the refrigerator. Paradoxically, alternating
poles decrease the magnetic field strength of the magnet
because the fields tend to cancel each other out as they
extend from the magnet. Thus, while alternating poles would
exert opposite forces on ions flowing through the magnetic
field, the decrease in magnetic field strength would lessen
any potential influence of the magnetic field on the target
ions. Nor does there appear to be any consensus in the industry
as to the ideal design for the pads. In fact, a competing
manufacturer asserts that, "Leading scientists agree
that unipolar magnets are superior to bi-polar,"35
although neither the scientists nor the supporting research
are identified.
Further proprietary
design information regarding at least one commercial source
of magnetic pads (BioflexTM pads) would also appear to be
irrelevant regarding biologic effects. Promotional information
for the pads indicates that the "concentric circle"
arrangement of the pads increases the likelihood that the
magnetic field would be applied perpendicular to flowing
blood, thereby maximizing the Hall effects. In fact, because
blood vessels run randomly throughout the three dimensions
of any tissue, there can be no "preferred" arrangement
of the magnetic field that would favor its perpendicular
orientation to the flow of blood.
Studies on
Static Magnetic Fields and Blood Flow
A number of studies have investigated the effects of static
magnetic fields on blood flow. Studies commissioned by the
makers of one type of magnetic pad showed that exposure
of a highly concentrated saline solution in a glass capillary
tube increased the flow of the solution. This study has
been often cited by manufacturers of static magnetic devices
as evidence that magnetic field therapy can potentially
affect the circulation of blood. Although the mechanism
for the increase in saline flow is not apparent, it certainly
could not have been related to any dilatory effect on the
walls of the glass capillary tube. The investigator who
performed the study concluded that the results of the experiments
performed using highly concentrated saline in a glass tube
should not be extrapolated to effects that would be expected
with flowing blood.36
A second study
evaluated the effects of the pads in the distal limbs of
horses using nuclear scintigraphy, a technique that is useful
in identifying areas of blood vessel dilation and inflammation.
That study concluded that, "Scintigraphy was performed
in the vascular, soft tissue, and bone phase using a cross
over trial to demonstrate increased blood flow and metabolic
activity as a result of the local application of a permanent
magnetic pad on the equine metacarpus. A highly significant
increase was evident in the three phases."37 The results
of this study have been used repeatedly to suggest that
magnetic pads promote blood circulation to the areas under
the pads.
This study,
which is apparently the only one to state that a static
magnetic field affects blood circulation, is open to criticism.
The experimental model, which compared the results of scans
on one "treated" limb vs. the non-treated limb
is inherently inaccurate, as one forelimb cannot be used
as a control for the other in scintigraphic studies (each
limb should be used as its own control). Furthermore, the
design of the study was flawed, as a bandage and magnetic
pad were applied to one limb while a bandage only was applied
to the other. A more appropriate control would have been
a bandage and a demagnetized pad. The radioisotope chosen
for the study was not appropriate to determine blood circulation
accurately. Finally, the study measured absolute scintigraphic
counts, when the use of relative perfusion ratios would
have been more appropriate.38
Numerous other
studies have failed to show any effect of magnetic fields
on blood circulation. For instance, no effect of dental
magnets on the circulation of blood in the cheek could be
demonstrated.39 Scintigraphic evaluation of blood flow in
mice exposed to two strengths of pulsating electromagnetic
field force failed to demonstrate any circulatory effects.40
A study on the circulatory effects of a magnetic foil was
unable to show any effect in the skin of human forearms41
and application of a magnetic foil to healing wounds in
rats showed no significant effects.42 A study in horses
showed that application of a magnetic pad over the tendon
region for 24 hours showed no evidence of temperature increase
in treated limbs vs. placebo controlled limbs, using thermographic
measurements as an indirect assessment of blood circulation
to the area.43
As a more practical
matter, if a magnet caused local increases in circulation,
one would expect the area under the magnet to feel warm
or become red as a result. Such an effect is not reported
when magnets are held in the hand. Furthermore, one would
expect any circulatory effects produced by very weak magnetic
fields to be magnified in stronger magnetic fields. However,
no circulatory effects have ever been reported in magnetic
resonance imaging machines, in which the magnetic forces
generated are two to four orders of magnitude greater than
those produced by therapeutic magnetic pads. In studies
of humans exposed to magnetic fields up to 1 Tesla (10,000
Gauss) there was no evidence of alterations in local blood
flow at the skin of the thumb or at the forearm.44 Even
a 10 Tesla magnetic field is predicted to change the vascular
pressure in a model of human vasculature by less than 0.2%,
and experimental results of the effects of strong magnetic
fields on concentrated saline solutions are in general agreement
with these predictions.45
Based on the
available scientific data, one must conclude that if there
is an effect of static magnetic fields on blood circulation,
there is no known biological mechanism by which that effect
is generated. One may also postulate that the boots, blankets,
and bandages in which the magnets are sewn have some sort
of a thermal effect that is independent of the magnetic
field (and could be duplicated with any form of bandaging).
Magnetic Fields
and Pain Relief
Both static
and pulsating electromagnetic field therapy have also been
promoted as being beneficial for the relief of pain. As
with other proposed effects, there is no known mechanism
of action by which application of a magnetic field produces
biological effects. If they are effective in the relief
of pain, it is unlikely that the effect is related to a
reduction in nerve conductivity; the field required to produce
a 10% reduction in nerve conductivity is roughly 24 Tesla.46
Studies evaluating
the effects of pulsating electromagnetic fields in the relief
of pain have shown conflicting results. Pulsating electromagnetic
field therapy has reportedly provided pain relief in the
treatment of osteoarthritis of the human knee and cervical
spine,47,48 in the treatment of persistent neck pain,49
and in the treatment of women with chronic refractory pelvic
pain.50 However, electromagnetic therapy showed no benefit
in the relief of pain due to shoulder arthritis51, and a
1994 summary of published trials of non-medicinal and noninvasive
therapies for hip and knee osteoarthritis concluded that
there were insufficient data available to draw any conclusions
on the efficacy of the therapy.52 Paradoxically, another
study in humans showed that magnetic treatment actually
induced hyperalgesia in a tooth pain model.53
Pads that apply
a static magnetic field are also promoted as having pain-relieving
effects. Poorly controlled studies from the Japanese literature
suggest that static magnetic devices were highly effective
in alleviating subjective symptoms such as neck, shoulder,
and other muscular pain.54,55 One controlled, double-blind
pilot study suggested that magnetic pads were effective
in the relief of myofascial or arthritic-like pain in postpolio
syndrome,56 although every patient in the study, whether
being treated with a placebo or a magnet, showed relief
from pain. However, other studies have concluded that a
magnetic foil offered no advantage over plain insoles in
the treatment of pain of the human heel57 and that a magnetic
necklace had no effect on neck and shoulder pain.58 It has
also been suggested that there is a strong placebo effect
at work in the perception of pain relief offered by static
Magnetic devices.59
Clinical Use
of Magnetic Fields in Veterinary Medicine
Magnetic and
electromagnetic devices appear not to be used on small animals.
However, the devices are widely advertised in magazines
targeted at horse owners. Pulsating electromagnetic field
therapy is typically applied to horses with boots or blankets.
Some of the variables of the magnetic field generated (such
as the amplitude and frequency of the signal) can be controlled
using this form of magnetic therapy. However, changes in
these variables appear to affect different tissues in different
ways, and those ways are not well defined, making selection
of ideal field strength of the therapy problematic.
The other way
to apply a magnetic field to a horse is by attaching a magnetic
pad. This form of therapy generates a continuous, static
magnetic influence on the targeted tissue; however, the
magnetic field cannot be modulated. The principle advantage
of this form of magnetic therapy is that it is relatively
inexpensive (compared to the cost of the machines) and easy
to apply; the disadvantage is that as yet there is no scientific
evidence of an effect.
The absence
of a plausible scientific theory for a mechanism of action
should never override reliable strong clinical evidence
of an effect. For example, the mechanism of aspirin was
not known for many years, although the drug was clinically
effective. However, there appear to be no published scientific
studies available that demonstrate that any form of magnetic
field therapy is valuable in the treatment of disease conditions
of the horse.
Daily electromagnetic
therapy did increase the concentration of blood vessels
in surgically created defects of equine superficial digital
flexor tendon, but the maturation of the repair tissue and
the transformation of collagen type (two essential components
in the healing process of tendon) actually were delayed
by the treatment in tendon samples collected at 8 to 12
weeks after surgery.60 No benefit could be demonstrated
in the healing of freshly created bone injuries treated
with pulsating electromagnetic field therapy when compared
to untreated control limbs, 61 although another study did
suggest an increase in bone activity under pulsating electromagnetic
field treatment when holes were drilled in horse cannon
bones.62 Topical treatment with a pulsed electromagnetic
field showed little effect on metabolism of normal horse
bone in another study.63 Unfortunately, the principle application
of pulsating electromagnetic field therapy in people, for
delayed and non-union fractures, is of little apparent use
in horses.
Callanetics
Where does
callanetics come from ?
American born Callan Pinckney developed the original programme
a few decades ago after training with Lotte Berk (now in
her mid 80s). Lotte Berk was a famous dancer and after a
severe back injury devised an exercise programme that kept
her and thousands of others fit, supple and strong into
old age.
Callan Pinckney
was born with scoliosis and during 10 years of backpacking
throughout the world developed further back and knee damage.
When she found the programme to be an incredible success
on herself, she started teaching other people. She has taught
thousands of people since then, all with great results.
Over the years Callanetics has been further developed and
refined, and after careful research more and more variations
to the original programme are introduced on a continuous
basis.
Is callanetics
safe ?
It is so safe that even eighty year olds can do these exercises.Originally
developed for bad backs, Callanetics uses small, delicate
movements consistently applied. Muscle groups are isolated
and worked at whilst the rest of the body is completely
relaxed. There is no sudden jerking or any hard impact,
which can cause harm to the body.
Is dieting
part of the callanetics programme ?
When doing Callanetics regularly, a person can wear clothing
two sizes smaller without shedding a kilo. Dieting is, therefore,
not part of the programme. However, if you lose 5 kg, it
will look as if you had lost 10 kg.
Is callanetics
easy ?
The exercises are hard work - at first. But they make you
feel spectacular! And one hour of Callanetics is equal to
24 hours of aerobic dancing in terms of tightening, pulling
up, and visible results.
Do you always
have to do a whole hour of the exercises in one session
?
If you do the exercises at home, the answer is no. You can
break an hour of exercises into 15 minute segments with
the same dramatic results.
Will it really
work ?
Within a few hours of Callanetics workouts you will have
the answer.
What are the
benefits of callanetics ?
Exercise, in general, promises strength, endurance and flexibility.
The Callanetics programme has nine additional benefits,
ie:
coordination
balance
comprehensive
body awareness
body control
discipline
speed
physical
and mental relaxation
builds
stamina
decreases
appetite 